Investigation of environmental pollutants and carbon nanotubes nanotoxicity on proteins.
Given the wide potential of nanoparticles such as carbon nanostructures and their biological and medical applications, It is essential to discuss their nanotoxicity in interactions with proteins and the negative effect of environmental pollutants on biomacromolecules leading to structural and functional changes. Recent studies have shown that carbon nanotubes and graphene, due to their small size, low density, high hardness, high strength, and excellent electrical properties, can be used for biological purposes such as cancer cell identification and destruction, tissue engineering, protein crystallization, manufacture of bioreactors and biosensors and pollutant absorbers. Due to biosafety concerns, the study of the interaction of carbon nanotubes with proteins could be key to finding more information in the field of nanotoxicology and designing biosensors used in various industries such as pharmacy, automotive and agriculture.
Among the proteins that can be used for this research are blood proteins, cancer proteins, thyroid receptors, and HSP. Therefore, studying the complex of carbon nanostructures and environmental pollutants with proteins will clarify the possibility of toxicity for proteins by these complexes. So, we aim to investigate the binding of these proteins to the complex of carbon nanotubes and various environmental pollutants in order to achieve the least structural and functional changes in biomacromolecules, especially these proteins.
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